English

學系成員

姚少凌 教授

  • 學歷
    國立清華大學化學工程系博士2000.9 至 2004.6
    經歷
    1. 元智大學 化學工程與材料科學學系 教授 (2018.08~Now)
    2. 元智大學 生物科技與工程研究所 合聘教授 (2018.08~Now)
    3. 中華民國基因檢測技術暨幹細胞研究發展協會 秘書長 (2017.01~Now)
    4. 財團法人 竹清化工文教基金會 董事/監事(2014.11~Now)
    5. 財團法人 李昭仁教授生醫工程發展基金會 董事/監事(2014.11~Now)
    6. 衛生福利部 桃園醫院 臨床倫理委員會 委員 (2016.03~Now)
    7. 衛生福利部 桃園醫院 醫學倫理及人體試驗委員會 委員 (2012.03~Now)
    8. 元智大學 化學工程與材料科學學系 副教授 (2014.02~2018.07)
    9. 元智大學 生物科技與工程研究所 合聘副教授 (2014.02~2018.07)
    10. 元智大學 化學工程與材料科學學系 助理教授 (2009.08~2014.01)
    11. 元智大學 生物科技與工程研究所 合聘助理教授 (2010.08~2014.01)
    12. 財團法人 食品工業發展研究所研究員(2004~2009)
    研究專長
    1. 細胞工程
    2. 組織工程
    3. 生化工程
    4. 幹細胞技術
    5. 生醫工程
    6. 轉譯醫學
    7. 細胞免疫療法
    得獎或研究成果
    1. 107學年度元智大學工學院「研究傑出獎」, 2020.
    2. 108年度應用型產學合作計畫-「產學成果特優獎」, 科技部工程司, 2019.
    3. 李長榮教育基金會第九屆「學術研究傑出青年教授獎」, 2019.
    4. 108-110年度「優秀年輕學者研究計畫」, 科技部, 2019.
    5. 106學年度元智大學工學院「研究傑出獎」, 2019.
    6. 2018台灣創新技術博覽會發明競賽「金牌獎」, 2018.
    7. 105學年度元智大學工學院「研究傑出獎」, 2018
    8. 106學年度元智大學產學合作計畫總件數「第一名」, 2018.
    9. 105學年度元智大學「研究傑出獎」, 2017
    10. 105學年度元智大學「輔導暨服務傑出獎」, 2017
    11. 106年度技術與知識應用型產學合作計畫-產學成果優良獎, 科技部工程司, 2017
    12. 2017台北國際發明暨技術交易展發明競賽「銅牌獎」, 2017
    13. 中華民國生醫材料及藥物釋放學會年會(財團法人李昭仁教授生醫工程發展基金會) 「年輕學者獎」, 2017
    14. 104學年度元智大學工學院「研究傑出獎」, 2017
    15. 科技部工程司 105年度應用型產學合作計畫-「產學成果特優獎」, 2016.
    16. 中華民國生醫材料及藥物釋放學會年會(李昭仁教授紀念研討會)「年輕學者組口頭論文競賽優等」, 2016
    17. 「SNQ國家品質標章-生物技術服務類」 (技轉與輔導再生緣生物科技) , 2015.
    18. 103學年度元智大學「教學傑出獎」, 2015
    19. 104年度科技部 「優秀年輕學者研究計畫」, 2015
    20. 科技部工程司 103年度技術及知識應用型產學合作計畫-「產學成果傑出獎」,2014
    21. 102學年度元智大學「青年學者研究獎」, 2013
    22. 101學年度元智大學「輔導暨服務傑出獎」, 2013
  • 期刊論文:

    1. Lin HD, Yao CL, Ou WJ, Luo YH, Chen SC*., “4-Aminobiphenyl suppresses homologous recombination repair by a reactive oxygen species-dependent p53/miR-513a-5p/p53 loop.” Toxicology 2020;444:152580.

    2. Lin HD, Wang FZ, Lee CY, Nien CY, Tseng YK, Yao CL, Chen SC*., “4-Aminobiphenyl inhibits the DNA homologous recombination repair in human liver cells: The role of miR-630 in downregulating RAD18 and MCM8.” Toxicology 2020;440:152441.

    3. Yao CL*, Lin CC, Chu IM, Lai YT., “Develop a surfactant-containing process to improved removal efficiency of phenol and control the molecular weight of synthetic phenolic polymer using horseradish peroxidase in aqueous system.” Applied Biochemistry and Biotechnology 2020;191(1):45-58.

    4. Lin KH, Chiang JC, Ho YH, Yao CL, Lee H*., “Lysophosphatidic acid and hematopoiesis: From microenvironmental effects to intracellular signaling.” International Journal of Molecular Sciences 2020;21(6):2015.

    5. Liu MY, Hua WK, Chiou YY, Chen CJ, Yao CL, Lai YT, Lin CH, Lin WJ*., “Calcium-dependent methylation by PRMT1 promotes erythroid differentiation through the p38α MAPK pathway.” FEBS Letters 2020;594(2):301-316.

    6. Yao CL*, Chi YW, Kao TT, Liu YL, Chiou TJ, Lai YT., “Effects of specific pathogen-free porcine platelet-rich plasma activated by the novel activator ectoine on cell proliferation and biological function.” Biochemical Engineering Journal 2020;153:107424.

    7. Lin CH, Lu JH*, Hsia K, Lee H, Yao CL, Ma H., “The antithrombotic function of sphingosine-1-phosphate on human adipose stem cell -recellularized tissue engineered vascular graft in virto.” International Journal of Molecular Sciences 2019;20(20):5218.

    8. Hsu SC, Lu LC, Chan KY, Huang CH, Cheng SL, Chan YS, Yang YS, Lai YT, Yao CL*., “Large-scale production and directed induction of functional dendritic cells ex vivo from serum-free expanded human hematopoietic stem cells.” Cytotherapy 2019;21(7):753-766.

    9. Hsia K, Lin CH, Lee H, Chen WM, Yao CL, Chen CC, Ma H, Wang SJ, Lu JH*., “Sphingosine-1-phosphate in endothelial cell recellularization improves patency and endothelialization of decellularized vascular grafts in vivo.” International Journal of Molecular Sciences 2019;20(7):1641.

    10. Juang LJ, Gao XY, Mai ST, Lee CH, Lee MC, Yao CL*., “Safety assessment, biological effects, and mechanisms of Myrica rubra fruit extract for anti-melanogenesis, anti-oxidation, and free radical scavenging abilities on melanoma cells.” Journal of Cosmetic Dermatology 2019;18(1):322-332.

    11. Chen Y, Yang XQ, Tseng BY, Tsai YH, Tseng SH, Lee CH, Yao CL*., “Deferoxamine preconditioning activated hypoxia-inducible factor-1α and MyD88-dependent Toll-like receptor 4 signaling in intestinal stem cells” Journal of Pediatric Surgery 2018;53(11):2349-2356.

    12. Juang RS, Chien CC, Yao CL, Yu SH, Sun AC*., “Preparation of magnetically recoverable mesoporous silica nanocomposites for effective adsorption of urea in simulated serum.” Journal of the Taiwan Institute of Chemical Engineers 2018;91:22-31.

    13. Yao CL*, Chen JH, Lee CH., “Effects of various monomers and micro-structure of polyhydroxyalkanoates on the behavior of endothelial progenitor cells and endothelial cells for vascular tissue engineering.” Journal of Polymer Research 2018;25(3):187.

    14. Chen Y, Tseng SH, Yao CL, Li C, Tsai YH*., “Distinct effects of growth hormone and glutamine on activation of intestinal stem cells” Journal of Parenteral and Enteral Nutrition 2018;42(3):642-651.

    15. Chen Y, Lee CH, Tseng BY, Tsai YH, Tsai HW, Yao CL*, Tseng SH*., “AZD8055 exerts antitumor effects on colon cancer cells by inhibiting mTOR and cell-cycle progression” Anticancer Research 2018;38(3):1445-1454.

    16. Lin KH, Li MW, Chang YC, Lin YN, Ho YH, Weng WC, Huang CJ, Chang BE, Yao CL*, Lee H*., “Activation of lysophosphatidic acid receptor 3 inhibits megakaryopoiesis in human hematopoietic stem cells and zebrafish.” Stem Cells and Development 2018;27(3):216-224.

    17. Kao CM, Wei SF, Chen SC, Yao CL, Ma C, Chien CC*., “Biotransformation of trinitrotoluene by Citrobacter sp. YC4 and evaluation of its cyto-toxicological effects.” FEMS Microbiology Letters 2018;365(1):fnx256.

    18. Tang BC, Yao CL, Xieh KY, Hong SG*., “Improvement of physical properties of poly(glycerol sebacate) by copolymerization with polyhydroxybutyrate-diols.” Journal of Polymer Research 2017;24(12):215.

    19. Lin YK, Sharma R, Ma H, Chen WS, Yao CL*., “In situ polymerizable hydrogel incorporated with specific pathogen-free porcine platelet-rich plasma for the reconstruction of the corneal endothelium.” Journal of the Taiwan Institute of Chemical Engineers 2017;78:65-74.

    20. Liao HY, Kao CM, Yao CL, Chiu PW, Yao CC, Chen SC*., “2,4,6-Trinitrotoluene induces apoptosis via ROS-regulated mitochondrial dysfunction and endoplasmic reticulum stress in HepG2 and Hep3B Cells.” Scientific Reports 2017;7:8148.

    21. Hsia K, Yang MJ, Chen W H, Yao CL, Lin CH, Loong CC, Huang YL, Lin YT, Lander AD, Lee H*, Lu JH*., “Sphingosine-1-phosphate improves endothelialization with reduction of thrombosis in recellularized human umbilical vein graft by inhibiting syndecan-1 shedding in vitro.” Acta Biomaterialia 2017;51:341-350.

    22. Cheng SL, Lin CH, Yao CL*., “Mesenchymal stem cell administration in patients with chronic obstructive pulmonary disease: state of the science.” Stem Cells International 2017;2017:8916570.

    23. Lin YK, Sugiri F, Chiu YH, Ma H, Lee CH, Yao CL*., “Industrial-scale processing of activated platelet-rich plasma from specific pathogen-free pigs and its effect on promoting human hair follicle dermal papilla cell cultivation.” Journal of the Taiwan Institute of Chemical Engineers 2017;71:28-37.

    24. Hsia K, Yao CL, Chen WM, Chen JH, Lee H*, Lu JH*., “Scaffolds and cell-based tissue engineering for blood vessel therapy.” Cells Tissues Organs 2015-16;202(5-6):281-295. (contributed equally as first author)

    25. Lee CH, Chen Y, Cheng CF, Yao CL, Wu JC, Yin WY, Chen JH*., “Incidence of and risk factors for pediatric metachronous contralateral inguinal hernia: analysis of a 17-year nationwide database in Taiwan.” PLoS One 2016;11(9):e0163278.

    26 Kao CM, Lin BH, Chen SC, Wei SF, Chen CC, Yao CL, Chien CC*., “Biodegradation of trinitrotoluene (TNT) by indigenous microorganisms from TNT-contaminated soil, and their application in TNT bioremediation.” Bioremediation Journal 2016;20(3):165-173.

    27. Lin KH, Ho YH, Chiang JC, Li MW, Lin SH, Chen WM, Chiang CL, Lin YN, Yang YJ, Chen CN, Lu JH, Huang CJ, Tigyi G, Yao CL*, Lee H*., “Pharmacological activation of lysophosphatidic acid receptors regulates erythropoiesis.” Scientific Reports 2016;6:27050.

    28. Yao CL*, Liao CJ, Liang SM., “Characterization and implantation of a novel foamy type of collagen SD rats to regenerate tissue by slowing down the collagen degradation rate.” International Journal of Polymeric Materials and Polymeric Biomaterials 2016;65(10):508-515. 

    29. Sin MC, Sun YM*, Yao CL, Chou CJ, Tseng HW, Zheng J, Chang Y*., “PEGylated poly(3-hydroxybutyrate) scaffold for hydration-driven cell infiltration, neo-tissue ingrowth, and osteogenic potential.” International Journal of Polymeric Materials and Polymeric Biomaterials 2015;64(16):865-878. 

    30. Mohamed MS, Chen Y, Yao CL*., “Intestinal stem cells and stem cell-based therapy for intestinal diseases.” Cytotechnology 2015;67(2):177-189.

    31. Ho YH, Yao CL, Lin KH, Hou FH, Chen WM, Chiang CL, Lin YN, Li MW, Lin SH, Yang YJ, Lin CC, Lu JH*, Tigyi G*, Lee H*., “Opposing regulation of megakaryopoiesis by LPA receptors 2 and 3 in K562 human erythroleukemia cells.” Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids 2015;1851(2):172-183.

    32. Hsu SH*, Ho TT, Huang NC, Yao CL, Peng LH, Dai NT., “Substrate-dependent modulation of 3D spheroid morphology self-assembled in mesenchymal stem cell-endothelial progenitor cell coculture.” Biomaterials 2014;35(26):7295-7307.

    33. Mohamed MS, Chen Y, Yao CL*., “A serum-free medium developed for expansion of murine intestinal stem cells in vitro.” Biotechnology Journal 2014;9(7):962-970.

    34. Yao CL*, Hsu SC, Hwang SM, Lee WC, Chiou TJ., “A stromal-free, serum-free system to expand ex vivo hematopoietic stem cells from mobilized peripheral blood of patients with hematological malignancies and healthy donors.” Cytotherapy 2013;15(9):1126-1135.

    35. Yao CL*, Lin YM, Mohamed MS, Chen JH., “Inhibitory effect of ectoine on melanogenesis in B16-F0 and A2058 melanoma cell lines.” Biochemical Engineering Journal 2013;78:163-169.

    36. Chen WC, Yu WJ, Chang CC, Chang JS, Huang SH, Chang CH, Chen SY, Chien CC, Yao CL, Chen WM, Wei YH., “Enhancing production of prodigiosin from Serratia marcescens C3 by statistical experimental design and porous carrier addition strategy.” Biochemical Engineering Journal 2013;78:93-100.

    37. Chen WC, Wei YH, Chu IM, Yao CL*., “Effect of the chondroitin sulfate C on the in vitro and in vivo chondrogenesis of mesenchymal stem cells in crosslinked type II collagen scaffolds.” Journal of Tissue Engineering and Regenerative Medicine 2013;7(8):665-672.

    38. Hua WK, Chang YI, Yao CL, Hwang SM, Chang CY, Lin WJ., “Protein arginine methyltransferase 1 interacts with and activates p38α to facilitate erythroid differentiation.” PLoS One 2013;8(3):e56715.

    39. Hsu SC, Wang LT, Yao CL, Lai HY, Chan KY, Liu BS, Chong P, Lee OK, Chen HW., “Mesenchymal stem cells promote neutrophil activation by inducing IL-17 production in CD4+ CD45RO+ T cells.” Immunobiology 2013;218(1):90-95. 

    40. Yao CL, Hwang SM., “Immortalization of human mesenchymal stromal cells with telomerase and red fluorescence protein expression.” Methods in Molecular Biology 2012;879:471-478 (ISBN: 978-1-61779-814-6).

    41. Chiang CL, Chen SSA, Lee SJ, Tsao KC, Chu PL, Wen CH, Hwang SM, Yao CL*, Lee H*., “Lysophosphatidic acid induces erythropoiesis through activating lysophosphatidic acid receptor 3.” Stem Cells 2011;29:1763-1773.

    42. Yen CL, Chen WJ, Lo ST, Chen KT, Yao CL, Lee TW, Lo JM., “Biodistribution of Tc-99m(I)-tricarbonyl labeled trastuzumab as an imaging agent for breast cancer with HER2 overexpression in an animal model.” Annals of Nuclear Medicine and Molecular Imaging 2011;24(3):119-122.

    43. Chen WC, Wei YH, Huang JB, Chu IM, Yao CL*., “Biological effects of oligosaccharide chondroitin sulfate C on human articular chondrocytes.” Biomedical Engineering-Applications Basis Communications 2011;23:245-252.

    44. Chen WC, Yao CL, Chu IM, Wei YH., “Compare the effects of chondrogenesis by culture of human mesenchymal stem cells with various type of the chondroitin sulfate C.” Journal of Bioscience and Bioengineering 2011;111:226-231.

    45. Chen WC, Yao CL, Wei YH, Chu IM., “Evaluating osteochondral defect repair potential of autologous rabbit bone marrow cells on type II collagen scaffold.” Cytotechnology 2011;63:13-23.

    46. Hung CJ1, Yao CL1, Cheng FC, Wu ML, Wang TH, Hwang SM., “Establishment of immortalized mesenchymal stromal cells with red fluorescence protein expression for in vivo transplantation and tracing in the rat model with traumatic brain injury.” Cytotherapy 2010;12:455-465. (contributed equally as first author)

    47. Chang YI, Hua WK, Yao CL, Hwang SM, Hung YC, Kuan CJ, Leou JS, Lin WJ., “Protein-arginine methyltransferase 1 suppresses megakaryocytic differentiation via modulation of the p38 MAPK pathway in K562 cells.” Journal of Biological Chemistry 2010;285:20595-20606.

    48. Chen TW, Hwang SM, Chu IM, Hsu SC, Hsieh TB, Yao CL*, “Characterization and transplantation of induced megakaryocytes from hematopoietic stem cells for rapid platelet recovery by a two-step serum-free procedure.” Experimental Hematology 2009;37:1330-1339.

    49. Chen TW, Yao CL, Chu IM, Chuang TL, Hsieh TB, Hwang SM., “Large generation of megakaryocytes from serum-free expanded human CD34+ Cells.” Biochemical and Biophysical Research Communications 2009;378:112-117. (contributed equally as first author)

    50. Kao IT, Yao CL, Chang YJ, Hsieh TB, Hwang SM., “Chondrogenic differentiation of human mesenchymal stem cells from umbilical cord blood in thermoreversible gelation polymer.” Chinese Journal of Physiology 2008;51:252-258. (contributed equally as first author)

    51. Chang CL, Lin ME, Hsu HY, Yao CL, Hwang SM, Pan CY, Hsu CY, Lee H., “Lysophosphatidic acid-induced interleukin-1β expression is mediated through Gi/Rho and the generation of reactive oxygen species in macrophages.” Journal of Biomedical Science 2008;15:357-363.

    52. Yeh HJ, Yao CL, Chen HI, Cheng HC, Hwang SM., “Cryopreservation of human limbal stem cells ex vivo expanded on amniotic membrane.” Cornea 2008; 27:327-333.

    53. Yao CL*, Hwang SM., “Ex vivo expansion of hematopoietic stem cells from human cord blood in serum-free conditions.” Methods in Molecular Biology 2007;407:165-175. (ISBN: 978-1-58829-744-0).

    54. Kao IT, Yao CL, Kong ZL, Wu ML, Chuang TL, Hwang SM., “Generation of natural killer cells from serum-free expanded human umbilical cord blood CD34+ cells.” Stem Cells and Development 2007;16:1043-1052. (contributed equally as first author)

    55. Yao CL, Feng YH, Lin XZ, Chu IM, Hsieh TB, Hwang SM., “Characterization of serum-free ex vivo-expanded hematopoietic stem cells derived from human umbilical cord blood CD133+ cells.” Stem Cells and Development 2006;15:70-80.

    56. Yao CL, Hwang SM., “Systematic strategy approach in medium design.” Experimental Hematology 2005;33:1273-1274 (Letter).

    57. Yao CL, Chu IM, Hsieh TB, Hwang SM., “A systematic strategy to optimize ex vivo expansion medium for human hematopoietic stem cells derived from umbilical cord blood mononuclear cells.” Experimental Hematology 2004;32:720-727.

    58. Yao CL, Liu CH, Chu IM, Hsieh TB, Hwang SM., “Factorial designs combined with the steepest ascent method to optimize serum-free media for ex vivo expansion of human hematopoietic progenitor cells.” Enzyme and Microbial Technology 2003;33:343-352.

     

  • (B)會議論文Conference Publications (Since 2011)

    1. Che-Chi Lin; I-Ming Chu; Chao-Ling Yao, "Development of a green process to remove phenol from wastewater and synthesis phenolic polymer by immobilizing enzyme", The 14th Asian Congress on Biotechnology 2019, NA~NA, (2019).
    2. Qing Yang; Chao-Ling Yao, "Development of a serum-free expansion medium for human mesenchymal stem cells", The 14th Asian Congress on Biotechnology 2019, NA, (2019).
    3. Yi-Ting Lai; Chao-Ling Yao, "Development of a serum-free induction medium for generation of monocytes from hematopoietic stem cells", 2019 International Advanced Drug Delivery Symposium & Annual Meeting of Biomaterials and Controlled Releases Society in Taiwan, PC-32, (2019).
    4. Yi-Ting Lai; Chao-Ling Yao, "Ex vivo a serum-free induction medium for monocytes from human hematopoietic stem cells", The 14th Asian Congress on Biotechnology 2019, NA~NA, (2019).
    5. Chao-Ling Yao, "Serum-free expansion and differentiation of human hematopoietic stem cells for cell therapy and immunotherapy", The 14th Asian Congress on Biotechnology 2019, S16-04, (2019).
    6. Qing Yang; Yu-Ting Wang; Chao-Ling Yao, "Serum-free induction of dendritic cells from human monocytes", 2019第十二屆桃園四校生命科技領域聯合學術研討會, B-02, (2019).
    7. En-Ling Hsieh; Stem Yi-Feng Hung; Chao-Ling Yao, "A serum-free freezing medium for hemopoietic stem cell cryopreservation", Cord Blood Connect, 5~5, (2018).
    8. Chun-hui Li; Chao-Ling Yao, "Culture of endothelial progenitor cells on poly (glycerol sebacate) and ectoine copolymer for vascular tissue engineering", 2018台灣幹細胞學會年會暨國際學術研討會, P5~01, (2018).
    9. Chun-Hui Li; Chao-Ling Yao, "Culture of endothelial progenitor cells on poly(glycerol sebacate) and Ectoine copolymer for blood vessel tissue engineering", 2018台灣化學工程學會65週年年會暨科技部化學工程學門成果發表會, BB005, (2018).
    10. Qing Yang; Yu-Ting Wang; Chao-Ling Yao, "Serum-free induction of human monocytes differentiation dendritic cells", 2018台灣化學工程學會65週年年會暨科技部化學工程學門成果發表, BB021, (2018).
    11. Yi-Ting Lai; Chao-Ling Yao, "Development of a serum-free monocyte induction medium for immunotherapy", 2018台灣化學工程學會65週年年會暨科技部化學工程學門成果發表會, BB070, (2018).
    12. Yi-Ting Lai; Chao-Ling Yao, "In vitro serum-free induction medium expanded monocytes from human hematopoietic stem cells", 2018台灣幹細胞學會年會暨國際學術研討會, P7-03, (2018).
    13. Qing Yang; Yu-Ting Wang; Chao-Ling Yao, "Inducing dendritic cells from human monocytes in a serum-free condition", 2018台灣幹細胞學會年會暨國際學術研討會, P2-02, (2018).
    14.  
    15. Chao-Ling Yao, "Stem cells, small molecules and polyhydroxyalkanoate scaffold for vascular tissue engineering", The 24th Symposium of Young Asian Biological Engineers’ Community, PA-16, (2018).
    16. Chao-Ling Yao, "造血幹細胞在細胞治療產業上的研發與應用", 智慧醫療與健康科技八校技術研討會, NA~NA, (2018).
    17. Yi-Chen Wei; Ku-Yu Xieh; Yi-Ting Lai; Chun-Hui Li; Yu-Ting Wang; Chao-Ling Yao, "Anti-melanogenesis effect of Ectoine on melanoma cell lines", 第十屆桃園四校生命科技領域聯合學術研討會, 75~75, (2017).
    18. Ku-Yu Xieh; Chang-Zhi Lin; Chao-Ling Yao, "Combination of mesenchymal stem cells and endothelial progenitor cells on electrospun polyhydroxyalkanoate scaffold for vascular tissue engineering", The 6th International Conference on Bio-based Polymers, 59~59, (2017).
    19. Chao-Ling Yao, "Combination of stem cells, small molecules, extracellular matrix and aligned electrospun polyhydroxyalkanoate scaffold for blood vessel tissue engineering", The 6th International Conference on Bio-based Polymers, 37~37, (2017).
    20. Chao-Ling Yao, "Cord Blood Expansion Technologies: An Update", Taiwan Regenerative Medicine Forum-Promising Applications of Cord Blood Stem Cell, 20~20, (2017).
    21. Ku-Yu Xieh; Chao-Ling Yao, "Culture of endothelial progenitor cells on poly(glycerol sebacate) and poly-3-hydroxybutyrate copolymer for vascular tissue engineering", The 2017 BEST Conference & International Symposium on Biotechnology and Bioengineering, 156~156, (2017).
    22. 文字方塊: 姚少凌Chao-Ling Yao

Yi-Chen Wei; Chao-Ling Yao, "Development of a serum-free freezing medium for hematopoietic cells", The 2017 BEST Conference & International Symposium on Biotechnology and Bioengineering, 158~158, (2017).
    23. Chao-Ling Yao, "Endothelial progenitor cells, small molecules, extracellular matrix and polyhydroxyalkanoate scaffold for blood vessel tissue engineering", The 13rd Asian Congress on Biotechnology 2017, 79~79, (2017).
    24. Ching-Min Chuang; Yi-Ting Lai; Yu-Ting Wang; Chao-Ling Yao, "Serum-free expanded human hematopoietic stem cells induce to monocytes in vitro", The 2017 BEST Conference & International Symposium on Biotechnology and Bioengineering, 155~155, (2017).
    25. Chao-Ling Yao, "Characterization and serum-free expansion of endothelial progenitor cells on surface modified polyhydroxyalkanoate scaffold for blood vessel tissue engineering", Tissue Engineering and Regenerative Medicine International Society-Asia Pacific Meeting 2016, S35-04, (2016).
    26. Chang-Zhi Lin; Ku-Yu Xieh; Chao-Ling Yao, "Co-culture of human mesenchymal stem cells and endothelial progenitor cells on aligned polyhydroxyalkanoate scaffold for blood vessel tissue engineering", 2016 Frontiers in Stem Cell Research and Cell Therapy & The 12th Annual Meeting of Taiwan Society for Stem Cell Research, 64~64, (2016).
    27. Wei-Chun Weng; Yi-Chen Wei; Chao-Ling Yao, "Design a serum-free induction medium for generation of human dendritic cells from monocytes", 2016 Frontiers in Stem Cell Research and Cell Therapy & The 12th Annual Meeting of Taiwan Society for Stem Cell Research, 65~65, (2016).
    28. Ching-Min Chuang; Chao-Ling Yao, "In vitro, inducting monocytes from serum-free expanded human hematopoietic stem cells", 2016 Frontiers in Stem Cell Research and Cell Therapy & The 12th Annual Meeting of Taiwan Society for Stem Cell Research, 60~60, (2016).
    29. Yi-Chen Wei; Wei-Chun Weng; Chao-Ling Yao, "Induction of human dendritic cells from monocytes under serum-free condition", 2016台灣化學工程學會63週年年會暨科技部化學工程學門成果發表會, BC031, (2016).
    30. Ku-Yu Xieh; Chang-Zhi Lin; Chao-Ling Yao, "The cross effect of co-culture of human mesenchymal stem cells and endothelial progenitor cells on aligned polyhydroxyalkanoate scaffold and their application for blood vessel tissue engineering", 2016台灣化學工程學會63週年年會暨科技部化學工程學門成果發表會, BC042, (2016).
    31. Chao-Ling Yao, "Blood Vessel Tissue Engineering: Combination of Endothelial Progenitor Cells, Extracellular Matrix and Aligned Electrospun Polyhydroxyalkanoate Scaffold", 李昭仁教授紀念研討會 2016年中華民國生醫材料及藥物制放年會」暨「海峽兩岸生物醫用材料與藥物遞送研討會」暨「2016 International Symposium on Theranostic Nanomedicine, (2016)
    32. Chang-Zhi Lin; Chao-Ling Yao, "Co-culture of cord blood-derived endothelial progenitor cells and mesenchymal stem cells on electrospun polyhydroxyalkanoate scaffold for vascular tissue engineering", The 2016 BEST Conference & International Symposium on Biotechnology and Bioengineering, (2016).
    33. Chao-Ling Yao, "Combination of endothelial progenitor cells, extracellular matrix and aligned eletrospun polyhydroxyalkanoate scaffold for vascular tissue engineering", International Society for Cellular Therapy 2016 Annual Meeting, (2016).
    34. Wei-Chun Weng; Chao-Ling Yao, "Development of a serum-free induction medium for generation of human dendritic cells from monocytes.", The 2016 BEST Conference & International Symposium on Biotechnology and Bioengineering, (2016).
    35. Ching-Min Chuang; Chao-Ling Yao, "Ex vivo induction of monocytes from serum-free expanded human hematopoietic stem cells", The 2016 BEST Conference & International Symposium on Biotechnology and Bioengineering, (2016).
    36. Chang-Zhi Lin; Ya-Ting Lin; Ku-Yu Xieh; Chao-Ling Yao, "Fixation of fibronection on aligned electrospun polyhydroxyalkanoate scaffold using surface modification method for vascular Tissue Engineering", 李昭仁教授紀念研討會 2016年中華民國生醫材料及藥物制放年會」暨「海峽兩岸生物醫用材料與藥物遞送研討會」暨「2016 International Symposium on Theranostic Nanomedicine, (2016)
    37. Xiangqin Yang; Yun Chen; Chao-Ling Yao, "Investigating the roles of hypoxia-inducible factor-1α and Toll-like receptor signaling pathway in the cultured crypt organoids with hypoxic preconditioning", 2015 International Conference on Stem Cells and Developmental Biology, (2015).
    38. Chao-Ling Yao, "Serum-free expansion of intestinal stem cells", 62nd TwIChE Annual Conference and 2015 Taiwan/Korea/Japan Joint Meeting on Chemical Engineering, (2015).
    39. Chao-Ling Yao, "Serum-free expansion, induction and application of human mesenchymal stem cells", 2015 Annual Congress of TSBT and TSHI, (2015).
    40. 文字方塊: 姚少凌Chao-Ling Yao

Ya-Ting Lin; Chang-Zhi Lin; Chao-Ling Yao, "Using surface modification method to immobilize extracellular matrix on aligned electrospun polyhydroxyalkanoate scaffold for vascular tissue engineering", 2015 International Conference on Stem Cells and Developmental Biology, (2015).
    41. Tai-Ju Hsu; Wei-Chun Weng; Jing-Min Chaung; Chao-Ling Yao, "Develop a serum-free freezing medium for human hematopoietic stem cells", 2015 International Conference on Stem Cells and Developmental Biology, (2015).
    42. Ya-Ting Lin; Chao-Ling Yao, "Immobilization of extracellular matrix on aligned eletrospun polyhydroxyalkanoate scaffold using surface modification method for vascular tissue engineering", The 2015 BEST Conference & International Symposium on Biotechnology and Bioengineering, (2015).
    43. Tai-Ju Hsu; Chao-Ling Yao, "Optimization of a serum-free freezing medium for human hematopoietic stem cells", The 2015 BEST Conference & International Symposium on Biotechnology and Bioengineering, (2015).
    44. Xiangqin Yang; Yun Chen; Chao-Ling Yao, "The hypoxic preconditioning activates hypoxia-inducible factor-1α and Toll-like receptor signaling pathway in the cultured crypt organoids", The 2015 BEST Conference & International Symposium on Biotechnology and Bioengineering, (2015).
    45. Ya-Ting Lin; Jian-Haw Chen; Chao-Ling Yao, "Application of the different processes of polyhydroxyalkanoate on vascular tissue engineering", The 20th Symposium of Young Asian Biochemical Engineers’ Community, (2014).
    46. Mohamed Shaaban Mohamed; Yun Chen; Chao-Ling Yao; Xiangqin Yang, "Characteristic and expansion of murine intestinal stem cells in a serum-free medium", Frontiers is Stem Cell Research and Regenerative Medicine & The 10th Annual Meeting of Taiwan Society for Stem Cell Research, (2014).
    47. Ya-Ting Lin; Jian-Haw Chen; Chao-Ling Yao, "Development of various monomers and micro-structure of polyhydroxyalkanoate on vascular tissue engineering", 2014台灣化學工程學會61週年年會暨科技部化學工程學門成果發表會, (2014)
    48. Ya-Ting Lin; Jian-Haw Chen; Chao-Ling Yao, "Effects of the different processes of polyhydroxyalkanoate on the behaviors of endothelial progenitor cells of application of vacular tissue engineering", Frontiers is Stem Cell Research and Regenerative Medicine & The 10th Annual Meeting of Taiwan Society for Stem Cell Research, (2014).
    49. Tai-Ju Hsu; Chia-Hsuan Mu; Chao-Ling Yao, "Optimization of a serum-free induction medium for human neutrophils derived from umbilical cord blood", The 20th Symposium of Young Asian Biochemical Engineers’ Community, (2014).
    50. Mohamed Shaaban Mohamed; Yun Chen; Chao-Ling Yao; Xiangqin Yang, "The development and application of a serum-free medium for murine intestinal stem cells", The 20th Symposium of Young Asian Biochemical Engineers’ Community, (2014).
    51. Mohamed Shaaban; Xiangqin Yang; Yun Chen; Chao-Ling Yao, "The research on novel formulation of a serum-free medium for the murine intestinal stem cells", 2014台灣化學工程學會61週年年會暨科技部化學工程學門成果發表會, (2014).
    52. Tai-Ju Hsu; Chia-Hsuan Mu; Chao-Ling Yao, "Utilized serum replacements to remove fetal bovine serum in human neutrophils induction medium", Frontiers is Stem Cell Research and Regenerative Medicine & The 10th Annual Meeting of Taiwan Society for Stem Cell Research, (2014).
    53. Tai-Ju Hsu; Chia-Hsuan Mu; Chao-Ling Yao, "Utilized the optimal serum-free expansion medium to induce the functional neutrophils from human hematopoietic stem cells derived from cord blood", 2014台灣化學工程學會61週年年會暨科技部化學工程學門成果發表會, (2014).
  • 專利:
    1. Hwang SM, Liu CH, Yao CL, Chu IM, Hsieh TB., Optimizing culture medium for CD34+ hematopoietic cell expansion. (US 8762074 B2, 2012/5/10-2032/5/10)

    2. Hwang SM, Yao CL, Hsieh TB, Chu IM., Stroma-free, serum-free, and chemically defined medium and method for ex vivo mononuclear cell expansion using the same. (US 7723106 B2, 2010/5/25-2027/1/28)

    3. Chen Y, Yao CL., 體外小腸幹細胞培養基及培養方法, Culture media and culture method for intestinal stem cells in vitro. (中華民國發明專利I522467, 2016/02/21-2034/05/07。中國專利CN 105087459A)

    4. 姚少凌, 魏毓宏., 具有相容性溶質之冷凍細胞保存組合物於人類造血幹細胞之應用. (中華民國發明專利 I681955, 2020/01/11-2037/03/06)

    5. 姚少凌., 不具胎牛血清之細胞冷凍保存組合物. (中華民國發明專利 I640630, 2018/11/11-2037/11/20)

    6. 姚少凌, 錡永文., 促進富含血小板血漿釋放生長因子之活化試劑. (中華民國發明專利 108127201, Under review)

    7. Lin WJ, Chang YI, Hua WK, Hung YC, Kuan CJ, Leou JS, Yao CL, Hwang SM., Use of protein arginine methyltransferases in regulating hematopoietic differentiation. (US20120282237A1, US Patent, Under review)

    8. Yao CL, Chen TW, Hwang SM., Media and processes for the ex vivo production of megakaryocytes from human CD34+ cells. (US 2010227401 A1, US Patent, Under review)

  • 1. 107學年度元智大學工學院「研究傑出獎」, 2020.

    2. 108年度應用型產學合作計畫-「產學成果特優獎」, 科技部工程司, 2019.

    3. 李長榮教育基金會第九屆「學術研究傑出青年教授獎」, 2019.

    4. 108-110年度「優秀年輕學者研究計畫」, 科技部, 2019.

    5. 106學年度元智大學工學院「研究傑出獎」, 2019.

    6. 2018台灣創新技術博覽會發明競賽「金牌獎」, 2018.

    7. 105學年度元智大學工學院「研究傑出獎」, 2018

    8. 106學年度元智大學產學合作計畫總件數「第一名」, 2018.

    9. 105學年度元智大學「研究傑出獎」, 2017

    10. 105學年度元智大學「輔導暨服務傑出獎」, 2017

    11. 106年度技術與知識應用型產學合作計畫-產學成果優良獎, 科技部工程司, 2017

    12. 2017台北國際發明暨技術交易展發明競賽「銅牌獎」, 2017

    13. 中華民國生醫材料及藥物釋放學會年會(財團法人李昭仁教授生醫工程發展基金會) 「年輕學者獎」, 2017

    14. 104學年度元智大學工學院「研究傑出獎」, 2017

    15. 科技部工程司 105年度應用型產學合作計畫-「產學成果特優獎」, 2016.

    16. 中華民國生醫材料及藥物釋放學會年會(李昭仁教授紀念研討會)「年輕學者組口頭論文競賽優等」, 2016

    17. 「SNQ國家品質標章-生物技術服務類」 (技轉與輔導再生緣生物科技) , 2015.

    18. 103學年度元智大學「教學傑出獎」, 2015

    19. 104年度科技部 「優秀年輕學者研究計畫」, 2015

    20. 科技部工程司 103年度技術及知識應用型產學合作計畫-「產學成果傑出獎」,2014

    21. 102學年度元智大學「青年學者研究獎」, 2013

    22. 101學年度元智大學「輔導暨服務傑出獎」, 2013

Back to Top